Passenger mutations finder

Me-PaMuFind-It

The Me-PuMaFind-It web tool allows scientists to easily get a list of potential passenger mutations present in any 129-derived transgenic mouse. To start a search with the 'Me-PaMuFind-It' tool, the user simply has to enter a gene symbol and choose the number of backcrosses. Next, the user will be given information that can be subdivided in four main parts:

  1. general information about the entered gene
  2. list of genes containing 129-derived protein coding variants that affect the entered gene
  3. list of genes containing 129-derived UTR and upstream variants that affect the entered gene
  4. list of genes that are affected by the entered gene in case it contains one or more 129-derived protein coding variants

variant_types

This web tool is based on sequences that were released by The Wellcome Trust Sanger Institute (Keane et al., 2011), version 3. The predictions made are indicative and should still be verified experimentally.

 

Tom.VandenBerghe@irc.vib-ugent.be and Peter.Vandenabeele@irc.vib-ugent.be for scienceIcon

Paco.Hulpiau@irc.vib-ugent.be and Liesbet.Martens@irc.vib-ugent.be for computerIcon

 

Citation: Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice

 
Variants in strain BL6NJ: Overview
Search for variants:
Number of backcrosses:
Number of backcrosses:
2 20
Current value: 0
Gene name:
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